721Decreasing Prevalence of Vancomycin-Heteroresistance (hVISA) among Methicillin-Resistant Staphylococcus aureus (MRSA) Blood Isolates over 10 years: Potential Impact of Vancomycin Treatment Guidelines
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721Decreasing Prevalence of Vancomycin-Heteroresistance (hVISA) among Methicillin-Resistant Staphylococcus aureus (MRSA) Blood Isolates over 10 years: Potential Impact of Vancomycin Treatment Guidelines
Methods. Standardized screening of MRSA blood isolates saved from 2002-2012 for hVISA and VISA on BHI agar supplemented with vancomycin 3 and 4 mg/L, respectively (previously shown to be the best screening method based on correlation with population analysis profile). One isolate was selected from each patient and trends were analyzed over time. Results. We encountered 1231 patients with SAB, M...
متن کاملVancomycin heteroresistance and methicillin-resistant Staphylococcus aureus.
Heteroresistance refers to the presence, within a larger population of fully antimicrobial-susceptible microorganisms, of subpopulations with lesser susceptibility. This phenomenon has been described in a wide range of microorganisms, but much recent attention has been directed toward its expression in Staphylococcus aureus. Although it has long been known that resistance to methicillin is char...
متن کاملPrevalence of Vancomycin Resistance in Methicillin-Resistant Staphylococcus Aureus
Background & Aims: Staphylococcus aureus is one of the most common pathogens in nosocomial infections. Vancomycin is the most important therapeutic drug of choice for treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains. Therefore, vancomycin-resistant Staphylococcus aureus (VRSA) or vancomycin-intermediate Staphylococcus aureus (VISA) strains are warning...
متن کاملMethicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Resistant Staphylococcus aureus (VRSA), and Vancomycin-Resistant Enterococci (VRE) contamination of food samples in Iran: A systematic review and meta-analysis
During the last years, antimicrobial resistance has become one of the greatest challenges in clinical settings. Staphylococcus aureus and Enterococcus are important nosocomial pathogens worldwide. In different corners of the world, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) have been isolated from various sources including different foods of an...
متن کاملVancomycin MIC plus heteroresistance and outcome of methicillin-resistant Staphylococcus aureus bacteremia: trends over 11 years.
Vancomycin MICs (V-MIC) and the frequency of heteroresistant vancomycin-intermediate Staphylococcus aureus (hVISA) isolates are increasing among methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) isolates, but their relevance remains uncertain. We compared the V-MIC (Etest) and the frequency of hVISA (Etest macromethod) for all MRSA blood isolates saved over an 11-year span and cor...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2014
ISSN: 2328-8957
DOI: 10.1093/ofid/ofu052.429